What you need to create a website on a website builder is a general knowledge of web design and an understanding of marketing, as well as integrations and business goals
Despite the absence of the need for a team of designers, programmers and sysadmins, to create a website on a website builder, you need some experience in working with these systems in order to avoid difficulties and problems, especially in integrations with APIs of external systems, such as web analytics, CRM, online payment, e-mail marketing, etc.